The Latin Poems of Margareta van Godewijck (1627-1677)

NpgRJ_NN_1561 1677..1683

Hippocampal area CA3 is widely considered to function as an autoassociative memory. However, it is insufficiently understood how it does so. In particular, the extensive experimental evidence for the importance of carefully regulated spiking times poses the question as to how spike timing–based dynamics may support memory functions. Here, we develop a normative theory of autoassociative memory ...

Mystic Poems, Poems of Enlightment

Dmd059204 1627..1639

The contribution of drug metabolites to the pharmacologic and toxicologic activity of a drug can be important; however, for a variety of reasons metabolites can frequently be difficult to synthesize. To meet the need of having samples of drug metabolites for further study, we have developed biosynthetic methods coupled with quantitative NMR spectroscopy (qNMR) to generate solutions of metabolit...

Op-brai140080 1627..1642

1 Department of Neurology, Yale University School of Medicine, New Haven, CT 06510, and Centre for Neuroscience and Regeneration Research, Veterans Affairs Medical Centre, West Haven, CT 06516, USA 2 Department of Neurology, University Medical Centre Maastricht, Maastricht, The Netherlands 3 Department of Clinical Genetics, University Medical Centre Maastricht, Maastricht, The Netherlands 4 Neu...

C2an36787d 1619..1627

Detection elements play a key role in analyte recognition in biosensors. Therefore, detection elements with high analyte specificity and binding strength are required. While antibodies (Abs) have been increasingly used as detection elements in biosensors, a key challenge remains – the immobilization on the biosensor surface. This minireview highlights recent approaches to immobilize and study A...